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R&D
R&D PUBLICATIONS
PUBLICATIONS

Aryl Sulfate is a Useful Motif for Conjugating and Releasing Phenolic Molecules : Sulfur Fluorine Exchange Click Chemistry Enables Discovery of Ortho-Hydroxy-Protected Aryl Sulfate Linker. Bioconjugate Chem. 2019, 30, 7, 1957–1968
Introduction of Para-Hydroxy Benzyl Spacer Greatly Expands the Utility of Ortho-Hydroxy-Protected Aryl Sulfate System : Application to Nonphenolic Payloads Bioconjugate Chem. 2019, 30, 7, 1969–1978
Sulfonate Version of OHPAS Linker Has Two Distinct Pathways of Breakdown : Elimination Route Allows Para-Hydroxy-Protected Benzylsulfonate (PHP-BS) to Serve as an Alternative Self-Immolative Group Bioconjugate Chem. 2020, 31, 5, 1392–1399
Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometric Assay Pharmaceutics. 2021 , 13 (1), 125

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